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Study overviews

Study Title: Surgical Ablation Versus No Surgical Ablation for Patients with Persistent or Longstanding Persistent Atrial Fibrillation Undergoing Mitral Valve Surgery

Current Status: Enrolling

Study overview

The purpose of the research is to determine whether surgical atrial fibrillation ablation performed during scheduled mitral valve surgery (surgery to repair a heart valve, a part of the heart which helps control the flow of blood) is better than mitral valve surgery by itself without the surgical ablation. Surgical ablation of atrial fibrillation is a technique used by surgeons to create scars in atrial heart tissue that block electrical signals that may be causing the heart to beat irregularly. People who have mitral valve disease requiring surgery and atrial fibrillation may take part in this research study.

For more information on this study, please click here.

GCO# 08-1078 IRB approved through 03/25/2011.


Study Title: Surgical Interventions for Moderate Ischemic Mitral Regurgitation

Current Status: Enrolling

Study Overview

The purpose of the research is to determine whether repairing a mitral valve (a heart valve which helps control the flow of blood) with moderate leakage (regurgitation), at the time of planned coronary artery bypass graft (CABG) surgery, will improve health outcomes of those who receive it compared to those who have the bypass alone. People who have coronary artery heart disease, requiring a CABG surgery, and have leakage (regurgitation) of the mitral valve may take part in this research study.

For more information on this study, please click here.

GCO# 08-1078 IRB approved through 10/9/10


Study Title: Evaluation of Outcomes Following Mitral Valve Repair/Replacement in Severe Chronic Ischemic Mitral Regurgitation

Current Status: Enrolling

Study Overview

The purpose of this research is to determine whether it is better to repair or replace the mitral valve (a heart valve which helps control the flow of blood) of patients with severe mitral valve leakage (regurgitation) from coronary artery disease. People who have mitral valve leakage (regurgitation), which may be severe, may take part in this research study.

For more information on this study, please click here.

GCO# 08-1078 IRB approved through 10/9/10


Study Title: Management Practices and the Risk of Infections Following Cardiac Surgery

Current Status: Enrolling

Study Overview

The purpose of the study is to determine the best ways to prevent infections after heart surgery. The study will only collect information about the care people receive during planned heart surgery. We call this kind of study an "observational study," because all we plan to do is observe the care you receive and how well you do during your treatment. People who have had or are scheduled to have heart surgery may take part in this observational study.

For more information on this study, please click here.

GCO# 08-1078 IRB approved through 11/19/10